Key Benefits of SeBaLIT™ Technology:
Enhanced Cellular Localization
SeBaLIT™ allows for precise identification of cellular components, improving our understanding of their distribution and function within different cellular compartments.
Detection of Protein-Protein Interactions
By enabling simultaneous labeling of multiple proteins, SeBaLIT™ aids in visualizing how proteins interact within the same cellular environment, revealing important insights into cellular signaling and mechanisms.
Real-Time Analysis of Dynamic Cellular Processes
The technology allows researchers to monitor cellular changes in real-time, enabling them to study dynamic processes such as migration, division, and response to stimuli with greater accuracy.
Increased Sensitivity and Multiplexing Capacity
SeBaLIT™ improves the signal-to-noise ratio, ensuring that low-abundance targets can be accurately detected without interference, while facilitating the use of several different fluorescent probes in a single experiment.
Overcoming Traditional Fluorescence Imaging Limitation
Traditional fluorescence methods often struggle with issues like spectral overlap or limited multiplexing capacity. SeBaLIT™ addresses these challenges by providing a more robust platform for capturing detailed, high-quality data from complex samples.
Laxco’s SeBaLIT™ multiplexing technology significantly enhances fluorescence imaging by overcoming the limitations of traditional methods. By enabling the concurrent detection of multiple targets within a single sample, SeBaLIT™ provides improved resolution and depth in cellular localization, offering researchers a clearer understanding of protein-protein interactions, cellular dynamics, and complex cellular responses.
SliPRO Series Microscope Multiplex
Image of BPAE cells stained with MitoTracker Red
CMXRos (Mitochondria), AlexaFluor 488 phalloidin
(F-Actin), DAPI (nuclei), 40x magnification
SliPRO Series Microscope Multiplex Imageof Mouse Kidney, cells stained with MitoTracker RedCMXRos (Mitochondria), 40x magnification
SliPRO Series Microscope MultiplexImage of BPAE cells stained with MitoTracker RedCMXRos (Mitochondria), AlexaFluor 488 phalloidin(F-Actin), DAPI (nuclei), 100x magnification (oil)